Black Fish Movie Assignment Example | Topics and Well Written Essays - 500 words

Black Fish Movie - Assignment Example There are no records of the attacks; thus trainers have little information on the risks involved in their job. The orcas are unhappy in this captivity and aggressive not to themselves but also to the trainers. This negligence witnessed in the way the orcas are treated, and this put the lives of the trainers in danger. The Blackfish film expounds on the mistreatment of orcas. This film focuses on the way the SeaWorld captured the orcas and kept in their captivity for human entertainment. Blackfish is one such documentary, which exposes the unkindness man imposes on animals and the plight of wildlife in marine parks as they undergo domestication and training to amuse humans and generate profits The filmmaker is making emphasis on telling the stories of the trainers and their narrative pointing to the abuse and in the way SeaWorld keep the killer whale in captive. The film advocates on the plight of orcas. It is not adequately supported because it is focusing on the incidents Tilikum and his captivity but fails to digress in talking the other incident involving others killer whales. There is no differentiation of the incidents. The film is not clear on how to treat SeaWorld. People interviewed in the film have the adverse opinion, and they do not provide the solution. The film has perfect visual work, and different interviews blended with the mixture of footage of animations of parks and animals. This cinematography is trying to bring clear vision and emotions on the subject of the plight of animals.

Snowmobiles Research Paper Example | Topics and Well Written Essays - 2250 words

Snowmobiles - Research Paper Example An interesting feature of a sled is the fact that it does not move on wheels. It has a long belt of rubber moving along the bottom of its body which forms a track for the sled to move on. Because of this track the sled does not slip and slide in the snow as it provides it with sufficient grip to keep it in control of the rider (DuBois 30). Snowmobiles use large amount of gasoline to run (Mara 1998). Hence, their popularity was greatly reduced during the 1970’s when the prices of gasoline reached sky high. Today there are only four major manufacturers of snowmobiles – Polaris, Arctic cat, Ski-doo and Yamaha (Mara 7). In snowmobiler’s parlance, these companies are called â€Å"big four† (DuBois 7). These companies manufacture these vehicles for various purposes which could be for personal use like transportation or for racers. Snowmobile racing is a very popular sporting activity during the snow fall season in various countries. This can be seen from the fac t that in North America alone there are more than 3000 clubs for snowmobilers (Mara 7). Major countries where people enjoy this sport are US, Canada, Denmark, Norway and Sweden. The cost of snowmobiles manufactured for this specific purpose is twice the price of ordinary use snowmobiles. Brief history of snowmobiles Snowmobiles were born out of the need for means of transport in snow covered areas. ... These were put to use for warfare in the World War II by the soldiers. Thus, though the early invention of this vehicle dates back to the 1920’s, it was mostly used for work and not for fun. It was only in the 1960’s that the idea of using them in sports caught the fancy of the inventors (Sommers 12). Carl Eliason built his first hand made Motor Toboggan in a small garage. He patented this machine in 1924. It was at that time made up of a long wooden sled and powered by 2.5 horse power engine which was attached on its outer board. Bicycle parts were used to make the dual trail track and it also had a radiator to cool the motor when it overheated (Sommers 11). Over a period of 15 years Eliason sold 24 such vehicles, each one being different from the other. His major buyers were the hunters and utility workers (Sommers 17). The biggest order of these vehicles (150 of them) was from the US army during the World War II. However, after this peak period there was a slowdown i n demand. By the 1950s, Canada became the production base for snowmobiles. However by this time, Eliason had a strong competitor, a superior quality product Ski-Doos which was invented by Joseph-Armand Bombardier and had taken over the snowmobile market with its unique design. This product had a design which still sets standards for today’s snowmobiles. A lot of inventors started taking interest in finding better and more efficient designs and â€Å"by 1972, there were more that 100 snowmobile companies† operating in this business (Sommers 19). However, as mentioned earlier, today the â€Å"big four† are the major players in this arena after an intense activity of mergers and acquisitions over the past three decades. Evolution of the designs The earlier design of snowmobiles was that of a sleigh

Critique on against gay marriage Essay Example for Free

Critique on against gay marriage Essay The modern world is experiencing transition in all aspects of life. This change is being experienced in marriage whereby some people are moving a way from the belief that marriage should only take place between people of same sex. They have gone to an extent of pushing for marriage between people of same-sex to be accorded the same treatment and recognition just like the case with the heterosexual marriage. Some people believe that marriage should be heterosexual while others believe that even homosexuals have a right to marry and live with their partners just like a husband and wife in opposite-sex marriage. This paper presents a critique in support of gay marriage. The society especially in the current state is crippling with many social problems emanating from heterosexual marriage. One of these problems is unwanted pregnancies which arise from irresponsible relationships. This is an incident which can only happen in a marriage between two people of opposite sex. Embracing same-sex marriage would offer a remedy to this problem because there is no chance of pregnancy in a marriage between gays and lesbians. This would also help in reducing the high cases of deaths and abortion which are being witnessed in the society today. Incase homosexuals decide to adopt a child, the possibility of neglect is very low as this would be a decision between two independent people. Same-sex marriage reduces the dominance by one partner which is associated with union between a man and a woman. For fear of victimization, most gays and lesbians are forced into heterosexual marriages against their will. However, they still continue to live their homosexual lives by secretly relating to other homosexuals while staying in the same-sex marriage. Therefore, accepting same-sex marriage will help reduce this unfaithfulness and promote marriage to one partner (Sullivan, A. , 2004). Since the society allows all kinds of people and groups to marry including murderers, thieves as well as marriage between people of different races. Condemning same-sex marriage is discrimination of the minority who are supposed to be protected by the constitution just like any other group. As opposed to what Bennet believes, it would not be the first time that the institution of marriage is experiencing change; Marriage between different races which are happening today never happened several years ago (Bennett, J. W. 1996). The strong position against homosexuality which is adopted by the church is an intrusion into private business. This is because marriage is a personal commitment between the two people involved in the relationship. This marriage therefore hurts no one who is not part of the relationship (Bennett, J. W. 1996). Every element of the society is transforming hence disregarding same-sex marriage is simply refusing to accept the natural changes in the institution of marriage. The acceptance of homosexuality as evident among school pupils is an indication that homosexuality is a thing of the current generation hence nature should be allowed to take its course. Bennet should not argue against adoption by gay and lesbian couples as this would be better that single parenting. The long-term repercussions of same-sex marriage talked about by those against gay marriage are baseless and coming out of fear of the unknown; accepting same-sex union would only serve to create more choices concerning marriage and people would be guided by individual choices. (Bennett, J. W. 1996). Conclusion From the accounts given above, same-sex marriage should be allowed and homosexuals do not deserve the harsh criticism and victimization that they are undergoing in the society. Legislation and rules governing marriage only needs to be adjusted to provide for same-sex union. Reference Bennett, J. W. (1996). Gay Marriage: Not a very good idea. The Washington Post. OP-ED; Pg. A19 Sullivan, A. (2004). Same-sex Marriage, Pro and Con: A Reader. New York: Vintage Books.

The Neurobiological Basis of Major Depressive Disorder (MDD)

The Neurobiological Basis of Major Depressive Disorder (MDD) Family name:  Batty Personal Name:  Therese Major depressive disorder (MDD) which is also known as either unipolar depression or major depression is a common yet disabling mental disorder affecting over 400 million people worldwide with a higher incidence in women than men (World Health Organisation, 2012). Depression may be endogenous where there is no discernible cause or reactive whereby the depression is a result of an incidence such as the loss of a parent, loved one or stress. Some of the emotions that individuals may experience with depression are, feelings of sadness, anger, bitterness and resentment, emotions which can last a few days or in some cases, months and have a huge impact on the individuals life. Some individuals suffering from MDD are also more likely to have a substance abuse problem, other mental and physical problems, and are likely to have a greater suicide risk. MDD is a widely researched topic with a sense of urgency to find the exact aetiology and pathophysiology behind the disease so that a more tho rough understanding can be reached and treatment can be uniquely designed for each individual. Researches surmise that various factors are involved such as the chemical changes in the brain, genetic predispositions and environmental factors. The aim of this essay, although not comprehensive enough, is to try and bring together research material from various sources and highlight some key areas around MDD such as a synopsis of the aetiology, pathophysiology, risk factors, treatments and test available today. Aetiology The underlying aetiology (causes) of MDD is so complex with many gaps that it appears that no-one is quite sure what causes depression, however much research done to date into this condition suggests that a combination of factors are involved, such as genetics, an individual’s biochemical environment, personal experiences and psychological factors. According to Dr Michael Miller, a Professor of Psychiatry at Harvard University (2013), several forces interact to bring on depression including faulty mood regulation by the brain, medications, medical problems, genetic vulnerability and stress. In as much as age related brain changes, disease related changes , for example, cerebrovascular disease, Parkinson’s disease, and epilepsy, lead to disruptions in the circuitry of emotion regulation and can cause the onset of depression (Wryobeck, Haines, Wynkoop and Swanson, 2013). Areas of the brain underpinned by major depressive disorders such as the thalamus, the hippocampus and the amygdala (Limbic circuitry) (Figure 1. Miller, 2013 ) include several groups of neurons and white matter. Cell connections, nerve cell growth, and the functioning of nerve circuits in the brain have a major impact on how the brain functions, particularly in the way they communicate with each other. Several different chemicals and hormones working within and outside these nerve cells play a key role, with reduced levels of serotonin and noradrenaline posit to be a huge factor associated with the disease (Miller, 2013). Similarly, Villanueva (2013) through the construct of a survey used to assess the neurobiology of MDD, found that brain-derived neurotrophic factor (BDFN) along with expressions of miRNA’s (involved in neural plasticity), abnormal gastrointestinal signalling peptides and proinflammatory cytokines are all causative factors of major depressive disorder. What proinflammatory cytokines do, is stimulate the hypothalamic-pituitary-adrenal axis, activate secretion of growth hormone and inhibits the thyroid stimulating hormone secretion, all of which are associated with depression. Whereas gut microbiota (flora), specifically leptin, ghrelin and cholecystokinin (signalling peptides), influence the central nervous system including modulation of neurogenesis which can influence brain chemistry and consequently an individual’s behaviour. According to Lopresti, Hood and Drummond (2013), as seen in figure 2 below, a bi-directional relationship is likely to exist between depression and lifestyle factors with key symptoms including changes in appetite, general energy levels, motivation levels and sleep, which in turn affect diet, exercise and sleep thereby creating a cycle of influence. A vicious cycle, all of which point to the necessity of promoting lifestyle changes Figure 2. Potential mechanism of diet, sleep and exercise on major depression. In Lopresti et al. (2013). Another avenue suggested by Dr Miller (2013), is that research has identified that genetics play a role, in that not only do certain genes make individuals more vulnerable to low moods, but it can influence how individuals respond to drug therapy. Likewise, Stanford school of medicine surmise that through its research on the study of identical (100% genetically identical) and non-identical twins (50% genetically identical) and major depression as a heritability factor, heritability shows to be a huge contributor in the development of this disease. Each individual inheriting a unique combination of genes, with a predisposition to certain illnesses (Levinson and Nichols, n.d.). Genes controlling either the production or utilization of serotonin plays and important role in the pathogenesis of depression and in particular with serotonin reuptake due to the fact that depressed individuals have a lower rate of serotonin uptake. In depression of the elderly or late onset depression, genetic s is less common or does not appear to play a role as genetic markers are not present (Halverson, Bhalla, Bhalla and Andrew (2014). In so saying then, non-genetic factors, many of which are not known, also need to be taken into account, as Levinson and Nichols (n.d) suggest, these factors also increase the risk and progression of depression. Pathophysiology Progression of the illness as indicated by Treadway et al.(2014), is linked to biological changes. Due to over-stimulation of steroidal and inflammatory signalling molecules by stress, structural abnormalities within the prefrontal cortex and hippocampus, known for regulating behaviour and endocrine responses to stress, can be damaged. Moreover diet, sleep and exercise not only play a significant role in the development and progression of the illness, it also impacts on the treatment. One research analysis undertaken by Maletic, Robinson, Oakes, Lyengar, Ball and Russell (2001), summarised that MDD involved structural, functional and molecular alterations within the brain. Similarly research conducted by Halverson et al. (2014), speculates that although the underlying pathophysiology of MDD has not been clearly defined, studies show a strong interaction between the neurotransmitter availability and receptor regulation, with emphasis again on serotonin activity disturbances in the cen tral nervous system. Other neurotransmitters such as epinephrine, dopamine, glutamate and brain derived neurotrophic factor (BDNF) are also implicated in depression. Cells within the hypothalamus are responsible for an individual’s emotional state which in turn link to the stress responses. Several studies , in particular Lopresti et al. (2013), show that during stressful times, the hypothalamic – pituitary-adrenal axis (HPA), the neuroendocrine circuit that manages stress in the body, becomes activated. This then leads to the release of epinephrine and glucocorticoids (cortisol) to assist the body in its adaptive response to stress. However, if the body remains under a constant state of stress, excitotoxicity of neurons, particularly in the hippocampus can occur leading to dendrite atrophy and apoptosis of neurons (Wryobeck et al. 2013). Research shows that while cortisol helps the brain to cope with stressful situations, it also damages and kills cells in the hippoca mpus. So it can almost be said that stress excites brain cells to death. Furthermore research shows that individuals experiencing depressive disorders have a smaller hippocampal volume than individuals who do not from depression and that positron emission tomographic (PET) showed a diminished activity in the area of the prefrontal cortex in individuals with depressive disorders. Thereby underlying the functional and structural abnormalities in the brain regions of individuals suffering from depression (Halverson et al. 2014). Most individuals with MDD present with normal appearance however, individuals with more severe symptoms may present with more significant signs such as, poor hygiene, poor grooming and changes in weight. Individuals with MDD have a distorted view of their life whereby negative attitudes make it more difficult to see a positive outcome from a difficult situation. Other symptoms such as psychomotor retardation, agitation or restlessness, suicidal thoughts or atte mpts, social withdrawal and in the elderly somatic complaints may also be evident. These however are only some of the underlying signs and symptoms as individuals vary from one to the next. Risk factors / causal agents It is a widely held view that there is an unambiguous relationship between physical, psychological, environmental, genetic and social factors as well as a dysregulated response to chronic stress as risk factors for depression. Halverson et al. (2014) infer that stress plays a dominant role in depression due to the chemicals involved throughout the body such as adrenaline and cortisol which in abundance, leads to other health complications. With the various types of onset of stress being for example, the loss of a parent prior to the age of 10 years, parent-child relationships, due to poor interaction between the two and child stressors, which can contribute to depression or thought to be associated with both early and late abuse and neglect. In addition, stressful changes in life patterns such as a serious loss, difficult relationships, trauma or financial problems can trigger a depressive episode. Women with a previous history of depression are at higher risk of menopausal depressio n while low testosterone levels in older men also aid in onset of depression (Halverson et al. 2014). Likewise Martin (2014) highlights that women may experience more episodes of depression than men due to hormonal changes such as during premenstrual phases, pregnancy, postpartum and menopause. Coupled with this is the additional stress of work-life balance where women take on the added responsibility of tending to children and or aging parents whilst still trying to forge a career for themselves. Individuals with a family history of depression tend to be at higher risk of developing depressive disorders. Psychosocial risk factors according to Halverson et al. (2014) can include impaired social supports, caregiver burden, loneliness, bereavement and negative life events. Abused substances and pharmacological agents can increase depression risks due to altering brain chemicals. These include pain relievers, sedatives, sleeping pills, cortisone drugs and seizure drugs, to name but a few. Whilst in the elderly, neurodegenerative diseases particularly Alzheimer’s and Parkinson’s, stroke, macular degeneration (vision) and chronic pain can all contribute to higher rates of depression (Martin, 2014). Treatment strategies First and foremost, education plays an important role in the treatment of MDD as individuals may become aware of the signs of relapse thereby allowing them to seek early treatment. Family and support members also need to be educated about the nature of depression and the treatment involved so as to be able to give the support needed, ensure medication compliance and encourage a change in lifestyle such as keeping active (Halverson et al. 2014). Wryobeck et al. (2013), posit that with depression being a multi-factored illness, treatment should encompass a combination of therapies such as psychotherapy, electroconvulsive therapy, lifestyle management, psychosocial therapy and pharmacotherapy. Pharmacotherapy such as anti-depressants being one method affects the neurotransmitters. Selective serotonin re-uptake inhibitors (SSRIs), a new class of antidepressants, which allow for the increase of serotonin by blocking the re-uptake of serotonin into the presynaptic neuron, is according to Clarke and Gordon (2011), used as the first line of treatment. SSRIs allow for autoreceptors to be desensitised or down-regulated, nerve transmission and serotonin levels are normalised and mood is elevated. Figure 3 below, illustrates how the amount of neurotransmitters in individuals with depression are reduced and postsynaptic receptors are increased as a response to these lower levels. The re-uptake of serotonin adding to the decreased amount of neurotransmitters. When treatment of SSRIs take place, serotonin levels increase due to the blocking of the re-uptake and down-regulation of postsynaptic receptors occur (Clarke Gordon, 2011). Figure 3 Action of selective serotonin re-uptake inhibitor drug. In neurobiology of mental illness Clarke Gordon (2011). Psychotherapy can include behaviour therapy, cognitive-behaviour therapy, family therapy, interpersonal therapy, psychodynamic psychotherapy and supportive psychotherapy. Psychosocial therapies according to Halverson et al. (2014) and supported by The American Psychiatric Association (APA) is often a first-line of treatment for mild cases of depression however, in more severe cases this should be combined with antidepressant medication. Other approaches according to Wryobeck et al. (2014) and Halverson et al. (2014), can include electroconvulsive therapy (ECT) which is thought to increase neurogenesis, reversing degeneration and decreased proliferation of nerve cells, regulate neurotransmitters and correct dysregulation of neuropeptides. Stimulation techniques such as vagus nerve stimulation which involves the nerve to be stimulated with electrodes resulting in the assumption that it may alter norepinephrine release and elevating levels of inhibitory GABA. Transcranial magnetic stimulation concentrates magnetic energy over parts of the brain allowing for either an increase or decrease in cortical excitability depending on the frequency. Stimulation over the right frontal lobe apparently reduces the symptoms of depression. Talk therapy as well as exercise are more non-invasive forms for dealing with MDD allowing the individual to develop problem solving skills, coping mechanisms and in some instances to form a suppor t group. Relevant tests To date there are no physical findings that are specific to MDD, instead diagnosis is dependent on the individual’s history and mental state exam. As depression may be linked to an underlying physical problem, both a physical exam as well as thyroid function blood tests can be done. A psychological evaluation is also of benefit to gather information around an individual’s feelings and behaviour pattern. In New Zealand a wide range of tools are available such as the Kessler 10 (K10) for assessing depression, anxiety and general mental health, the patient health questionnaire (PHQ-9) for depression and the GAD-7 for anxiety assessment. According to the Best Practice Advocacy of New Zealand [bpac z](2009) these tools also allow for monitoring the response to an individual’s treatment regime to ensure that optimal health is being met. In conclusion, to date the specific causes of major depressive disorders (MDD) is still unknown, however a substantial amount of research has gone into and still continues in this area with a consensus that depression appears to be a multifactorial and diverse group of disorders involving the chemical reactions and nerve communication in the limbic circuitry of the brain and both genetic and environmental factors. Progression of MDD is linked to biological changes, diet, sleep and exercise. Treatment strategies appear to be multi-factored with underlying assumptions based on individual research results. Education is still an important element focusing on the individual and support structures while more up to date pharmacopeia such as serotonin re-uptake inhibitors, lead the market as the go to drug for antidepressants. Most literature to date however, underlines the need for more research to take place, in particular, within the area of the aetiology / pathophysiology of the disease and likewise specifically structured individual treatment strategies. References Clarke, G. Gordon, C. (2011). Neurobiology of mental illness. In J. Craft, C. Gordon A. Tiziani (Eds.), Understanding pathophysiology (pp. 1177-1180). Chatswood, NSW: Elsevier. Halverson, J. L., Bhalla, R. N., Bhalla, P. M. Andrew, L. B. (2014). Depression. Retrieved from http://emedicine.medscape.com/article/286759. Levinson, D.F. Nichols, W.E. (n.d.). Major depression and genetics. Retrieved from http://depressiongenetics.stanford.edu/mddandgenes.html. Lopresti, A. L., Hood, S. D. Drummond, P. D. (2013). A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise. Journal of Affective Disorders 148 (2013), 12-27. Maletic, V., Robinson, M., Oakes, T., Lyengar, S., Ball, S. G. Russell, J. (2007). Neurobiology of depression: an integrated view of key findings. International journal of Clinical practice, 61 (12), 2030 – 2040. doi: 10.1111/j.1742-1241 Martin, B. (2014). What are the risk factors for depression? Retrieved from http://psychcentral.com/lib/what-are-the-risk-factors-for-depression. Miller, C. M. (2013). What causes depression. Retrieved from http://www.health.harvard.edu/newsweek/what-causes-depression.htm. The Best Practice Advocacy centre of New Zealand. Assessment of depression in adults in primary care. (2009). Retrieved from www.bpac.org.nz/BPJ/2009/adultdep/assessment.aspx. The world health organisation. (2012). Depression fact sheet. Retrieved from www.who.int/mediacentre/factsheets. Treadway, T. M., Waskom, M. L., Dillon, D. G., Holmes, A. J., Park, M. M., Charavarty, M. M., ‘†¦Ã¢â‚¬â„¢, Pizzagalli, D. A. (2014). Illness progression, recent stress and morphometry of hippocampal subfields and medial prefrontal cortex in major depression. Society of Biological Psychiatry. Retrieved from http://dx.doi.org/10.1016/j.biospych.2014.06.018 Villanueva, R. (2013). Neurobiology of major depressive disorder. Neural Plasticity, volume 2013. doi: 10.1155/2013/873278 Wryobeck, J. M., Haines, M. E., Wynkoop, T. F. Swanson, M. M. (2013). Depressive disorders. In C. Noggle S. Dean (Eds.). The Neuropsychology of psychopathology (pp 201-220). New York, NY: Springer Publishing. List of illustrations Figure 1. Miller, C. M. (2013). What causes depression. Retrieved from http://www.health.harvard.edu/newsweek/what-causes-depression.htm. Figure 2. Lopresti, A. L., Hood, S. D. Drummond, P. D. (2013). A review of lifestyle factors that contribute to important pathways associated with major depression: Diet, sleep and exercise. Journal of Affective Disorders 148 (2013), 12-27. Figure 3. Clarke, G. Gordon, C. (2011). Neurobiology of mental illness. In J. Craft, C. Gordon A. Tiziani (Eds.), Understanding pathophysiology (pp. 1177-1180). Chatswood, NSW: Elsevier.

Alzheimer’s Disease Essay examples -- Alzheimers Disease Essays

Alzheimer’s disease is a neurodegenerative disorder affecting memory, cognitive and non-cognitive functions. Studies show that most cases of Alzheimer’s disease pertains to people who are 60 years of age or older; meanwhile, 80% of these cases are due to genetics. The risk of one having Alzheimer’s disease varies with their age and ethnicity. That being said, some elders are obtaining this disease in very late life, nearing their 90’s. The gene that is usually responsible for Alzheimer ’s disease (AD) is the Apolipoprotein E (APOE gene) which gets its name from encoding for the protein Apolipoprotein. It is on chromosome 19 and has three main alleles on the gene that seem to be responsible for this disease. They are: ÃŽ µ2, containing cysteine at position 112 and arginine at position 158 of the gene, ÃŽ µ3 containing cysteine at both 112 and 158 positions, and ÃŽ µ4 containing arginine at both 112 and 158 positions of the gene. The APOE ÃŽ µ4 allele is the disease’s most prevalent allele. The APOE ÃŽ µ4 allele is the disease’s most prevalent allele. The function of this gene is to regulate cholesterol and triglyceride metabolisms. This shows it is not only coincidental that high cholesterol and diabetes lead to late-onset Alzheimer’s. The APOE ÃŽ µ4 allele was tested and discovered to be so dangerous in 1993. Since, many more studies have been completed on this allele and it has been known to be the main cause of Alzheimer’s disease. Once all the human genotype was known after using the Human Genome Project, a microarray system used to study over 80 percent of the Caucasian genome for association signals called the 500K GeneChip from Affymetrix was created. This microarray kit was used to confirm that using high-density single nuc... ...sion, the results point researchers in the right direction proving that late on-set Alzheimer’s is very closely related to this APOE locus, especially the ÃŽ µ4 allele. Further studies may also show that this allele will likely contribute to other diseases as well. With the use of ultra-high density genome, further associations will be made regarding the link between late on-set Alzheimer’s and the APOE locus. Works Cited Coon, Keith D. Ph.D.; Amanda J. Myers, Ph.D.; David W. Craig, Ph.D.; Jennifer A. Webster, B.A.; John V. Pearson, B.Sc.; Diane Hu Lince, Ph.D.; Victoria L. Zismann, M.S.; Thomas G. Beach, M.D.; Doris Leung, M.D. â€Å"A High-Density Whole-Genome Association Study Reveals That APOE Is the Major Susceptibility Gene for Sporadic Late-Onset Alzheimer’s Disease.† Physicians Post Graduate Press. J Clin Psychiatry 68:4, April 2007: 613-618. (Print)

Characterization of Elizabeth and Mr. Darcy in Jane Austens Pride and

Characterization of Elizabeth and Mr. Darcy in Jane Austen's Pride and Prejudice      Ã‚  Ã‚   Elizabeth Bennet, the heroine of Jane Austen's Pride and Prejudice, is an authentic character, allowing readers to identify, sympathize, and grow with her. Unfortunately, Austen does not create a match for Elizabeth who is her equal in terms of characterization. Mr. Darcy, Elizabeth's sometime adversary, beloved, and, finally, husband, is not so carefully crafted as she, for his character is somewhat undefined, made up of only mystery, inconsistency, and conventionality.    Elizabeth is, initially, quick to make judgments and just as quick to hold fast to those preconceptions. In effect, Elizabeth represents both aspects of the novel's title, being both proud and prejudicial. It is not these factors, then, that endear her to readers, but rather the depth of her character in that she develops into a more even-minded person with a rare capacity for self-awareness. For though at one time she has the highest regard for Mr. Wickham and a low opinion of Mr. Darcy, later, though it is her "greatest misfortune" (Austen 61), Elizabeth amends her former thinking by "feeling that she had been blind, partial, prejudiced and absurd" (135). It is evident that she matures into a fully developed woman who can admit, "'Till this moment, I never knew myself'" (135, emphasis mine).    Mr. Darcy is truly an enigma. Though he is apparently handsome, his physical attributes are nondescript; readers may learn more about this powerful figure's person and tastes from the description of Pemberley, his grand estate. If Pemberley is indeed an extension of, or a reflection of, Mr. Darcy, Elizabeth's pondering that "to be mistress of Pemberley might be so... ... "exactly the man, who, in disposition and talents, would most suit her" (Austen 199).    Works Cited Auerbach, Nina. "Waiting Together: Pride and Prejudice." Pride and Prejudice. By Jane Austen. Ed. Donald Gray. New York: Norton and Co., 1993. pp. 336-348. Austen, Jane. Pride and Prejudice. 1813. Ed. Donald Gray. New York: Norton and Co., 1993. Harding, D. W. "Regulated Hatred: An Aspect in the Work of Jane Austen." Pride and Prejudice. By Jane Austen. Ed. Donald Gray. New York: Norton and Co., 1993. pp. 291-295. Johnson, Claudia L. "Pride and Prejudice and the Pursuit of Happiness." Pride and Prejudice. By Jane Austen. Ed. Donald Gray. New York: Norton and Co., 1993. pp. 367-376. Mudrick, Marvin."Irony as Discovery in Pride and Prejudice." Pride and Prejudice. By Jane Austen. Ed. Donald Gray. New York: Norton and Co., 1993. pp. 295-303.

Implementing Effective Job Delegation in the Units Essay

As a supervisor on our medical surgical unit, our hospital patient satisfaction scores for the past two years have been going down and there is a great need to improve patient satisfaction scores, particularly in the area of effective job delegation. Research (2011) has shown that a leader who does not delegate might likely feel stressed and overloaded. Although it might seem the best way for work to get done, is to do it yourself, but it’s not a good long-term solution. Feedback and review remain helpful and important, although the relationship is more likely one of mentoring, rather than coaching. The Question In order to improve patient satisfaction score in hospitals, the first question that health care providers should ask is what can be done to improve the quality of care given to our patients, and the second question is, how can effective job delegation improve our patient satisfaction score in our hospital? Will the creation of a policy on implementation of effective job delegation, encourage collaboration between the nursing staff and personnel to ensure that all personnel are not stressed or overworked? On our medical surgical unit, nurses struggle to deliver all the care their patients need, but are unable, due to stress and overwork. Good delegation saves time, develops people, grooms a successor, and motivates. Poor delegation will cause frustration, discouragement and Confusion, as such the delegated person will fail to carry out the delegated task. Effective job delegation will improve our patient satisfaction scores, even if most nurses would prefer to deliver all the care their patients need, but can’t, due to overwork and stress. The delegated task may be small, but has a large overall impact for all those involved. Nursing is a demanding profession, often nurses feel as though there are not enough hours in the day to complete all tasks, delegation of job will help nurses complete all the jobs allocated, this will help improve patient’s satisfaction scores. In the medical field today there is shortage of nurses, but still nurses are still expected to provide safe and effective care for their patients, by elegating some aspects of care to others this goal can be archived. Evidenced-Based Studies Many studies have been performed on effective job delegation. An article by American Nurses Association: Research and expert opinions suggest that effective job delegation frees up Nurses to do what they have been educated to do and coordinate patient care (ANA, 2020). It explained that delegating jobs help improve collaboration between healthcare workers, by delegating some aspects of care to others. Another article in the ADVANCE web site published by trustworthy researchers, who did the research on: why it is significant for healthcare workers to delegate job: since they decided what patient care intervention is necessary and how, when, and by whom these interventions need to be provided. The article narrated how effective job delegation will improve patient satisfaction scores; though most nurses would prefer to deliver all the care their patients need (Juno, 2010). An advanced research was carried out by nursing expert, who explained, that effective job delegation will improve patient satisfaction scores due to nurses shortage and the need to lower medical cost. The article describes how good job delegation saves time, develops people, grooms a successor, and motivates workers, while Poor job delegations causes frustration and overwork to nurses, making the task of healthcare workers difficult to give safe healthcare to their patients ( Juno, 2010). It explained that delegating jobs help improve collaboration between workers. An international research in South Africa discovered that there is a large disparity in service levels workload, between private and public sectors. The research point out that effective job delegation is necessary for both private and public sectors for jobs to be carried out efficiently (AFN, 2012). The organization Advocate for Nurses carries out a research and found out that the provision of health care in America has been compromised by the loss of trained health workers due to over work and stress, the article explained that when Managers or leaders engage in effective job delegation in the health care organization, Nurses will not leave the profession because of overwork and stress. It explained that poor job delegation lead to pressure and work overload, because most nurses think they can provide all the care their patient need, which is impossible to do, as such leaving one tressed, unhappy, and feeling that you’re letting your profession down, the solution to prevent this feeling is effective job delegation (AFN, 2012). They also explained why health care worker have to delegate, because of changes in healthcare delivery, they stressed the fact that task delegation is here to stay at least for the foreseeable future. Job delegation is crucial to cost containment a nd Job delegation is important; as such health care professionals should take it as an expected professional nursing activity (AFN, 2012). The Proposal The outcome of creating a policy is something that is realistically obtainable in a professional practice: Access to the hospital policies, meeting with floor managers/unit leaders and Identifying problems in our hospital have shown that our nurses and managers are stressed and overworked. The task of a competent manager is not to do all the work on his or her own, but to smartly deliver within the given parameters of budget and timeline I propose that all managers must make sure that the delegated person understands the importance of the task, the responsibility it brings and the long-term consequences. Once they are clear about the task it becomes easy for the job to be accomplished. Managers should make sure, those who are delegated, feel they are contributing to the success of the organization rather than standing on the periphery, and they must ensure that the job being delegated is handed to the appropriate individual, because if the task is not done, the person who delegated the job as well as the delegated person are responsible for non-performance of the job. Delegation is transferring a competent individual the authority to perform selected tasks in a selected situation. Effect job delegation facilitates success and trust among nurse, who then be able to deliver safe and satisfactory care of patients, as a result improve patient’s satisfaction scores. Conclusion Effective delegation involves achieving the desired results, managing the demanding deadlines, empowering and equipping the team. Ultimately, the responsibility of getting delegated job accomplished remains with the manager. Researchers have shown that leaders who do not delegate feel stressed and overloaded with work. Good delegation saves time, develops people, grooms a successor, and motivates. Poor delegation will cause frustration, discouragement and confusion. Effective job delegation strategies incorporated into health care practice can provide health care workers with more time for professional nursing roles, and enhance job satisfaction in the areas of decision-making and promotional opportunity.